A decline in glycolytic ATP production is the fundamental mechanism limiting lifespan; species with an optimal rate of decline over time survived

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By appropriately scaling the perturbation amount for each colour channel separately, we can also extend this to work with palettes where is different for each colour component, provided that they are still regularly spaced. Unfortunately, the less regular the palette is, the less effective this technique becomes. If we wish to leverage the strengths of ordered dithering for use with irregular or arbitrary palettes, a more general solution is needed.

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In rare cases chicken pox can cause a swelling of the brain, called encephalitis; an inflammation of the lungs, called pneumonitis; and stroke, which can result in hospitalisation and - very rarely - death.